Sjogrens syndrome is an autoimmune disorder a disorder in which your body attacks its own tissues because it thinks they are foreign. It prevents your bodys exocrine (moisture-producing) gland from producing enough moisture for different areas of your body. This leads to chronic and lifetime dryness. Sjogrens syndrome affects many areas of your body. In addition to the mouth and eyes, other affected areas include the skin, vagina, respiratory tract (lungs), and gastrointestinal tract (stomach and intestines).

Even the pancreas and sweat glands may be affected.

People at risk include:

Females who constitute about 90 per cent of patients

People over the age of 40 years

Those who have other autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, and scleroderma

People on medications for allergies, high blood pressure, and depression

People who have undergone radiation therapy

Patients who have had bone marrow transplant

A common symptom of Sjogrens syndrome is dryness that losts a long time. Dryness may lead to other serious medical conditions including:

Eyes (corneal ulceration, serious infections)

Mouth (increased incidence of cavities, bronchitis, pneumonia)

Rarely, in patients who have serious autoimmune Sjogrens problems, the kidneys may be affected. A small percentage of patients will develop lymphoma.

The symptoms of Sjogrens syndrome are sometimes hard to recognize because they take a long time to develop and may look like signs of other medical conditions.

Evaluation by an experience rheumatologist is recommended.